I’ll take the first two. This stuff is my specialty.
1. According to OSHA, the recommend allowable limit of CO2 for an 8 hour work day shouldn’t exceed 5,000 ppm (0.5% saturation). Although for infants and older folks, it’s a lot less.
As far as for short term exposure, NIOSH sets the limit is 30,000 ppm (3% saturation) but warns that any exposure at 4% saturation or higher is immediately dangerous.
2. OSHA sets the standard for minimum O2 level at 19.5% but doesn’t take into consideration the several factors that must be accounted for including elevation, temperature, barometric pressure, and the overall condition of the people involved.
For example, someone at 10,000 ft above sea level can begin to feel the effects of hypoxia even though there’s 20% oxygen saturation due to the fact that there isn’t enough pressure to force the oxygen cells through the wall of the lungs. Also, someone that smokes a half a pack a day, will feel the effects of hypoxia before a non-smoker due to the carbon monoxide being carried by the hemoglobin (red blood cells). The CO causes the O2 molecules to bond to the blood cells and won't let them go. The cells then just carry oxygen around and never deposite it anywhere. This is called Hypoxemic hypoxia.
And one who drinks alcoholic beverages regularly or has just had a drink will suffer from Histotoxic hypoxia before a healthy individual will. The quantity of oxygen reaching the cells is normal, but the cells are unable to effectively use the oxygen due to disabled oxidative phosphorylation enzymes.
Dude, my crew chief SI would be proud….